3D-Printed Brachial Plexus Model for Thoracic Outlet Syndrome

9th July 2025

Summary of the Case Study published by the 3D Printing in Medicine Journal 

In this case study published by the 3D Printing in Medicine Journal, a multidisciplinary team from the Hospital for Special Surgery (HSS) collaborated to create a patient-specific 3D printed model of the brachial plexus and surrounding bones using MRI-only imaging, avoiding any exposure to ionizing radiation. The team used GE HealthCare’s advanced MR neurography and zero-echo time (ZTE) MRI sequences to visualize both nerve and bone structures. The imaging data was then processed by Axial3D, whose AI-powered segmentation platform automatically converted the scans into a detailed 3D model—supporting precise diagnosis, treatment planning, and patient communication.

Overview of the Study

  • A 28-year-old patient, suspected of having neurologic thoracic outlet syndrome (TOS), underwent detailed MRI scanning—MR neurography for nerves and zero‑echo time (ZTE) for bones—on GE HealthCare’s 3 Tesla platform.
  • Axial3D’s cloud-based INSIGHT software processed the images: automatically uploading, de‑identifying, segmenting nerves and bones, and verifying results—all within a streamlined workflow .

Key Benefits of the 3D Model

  • Anatomical clarity: The full-color 3D-printed model clearly demonstrated a first-rib synostosis compressing the T1 nerve root, providing precise spatial context that was difficult to appreciate on imaging alone.
  • Informed treatment planning: With the model confirming the diagnosis, the care team opted for a targeted physical therapy regimen instead of surgery—leading to significant symptom relief within weeks.
  • Radiation-free precision: Using only MRI data, the model offered an accurate, detailed representation of both nerve and bone anatomy, eliminating the need for additional CT imaging or radiation exposure.
  • Improved patient engagement: The tactile model made it easier for clinicians to communicate the condition and treatment plan, increasing patient understanding, trust, and adherence.
  • Stronger clinical decision-making: By visualizing complex anatomy in 3D, the care team was able to plan more confidently, collaborate across specialties, and deliver a more personalized care approach.

GE HealthCare × Axial3D Collaboration

This study exemplifies the transformative benefits of our collaboration with GE HealthCare:

  • Integrated MRI workflow: Utilizing GE HealthCare’s neurography and ZTE sequences, data is seamlessly fed into Axial3D’s AI-powered segmentation (Axial3D INSIGHT™) to create detailed patient-specific models
  • Radiation-free modeling: Eliminates the need for additional CT scans, reducing radiation exposure and streamlining the patient experience
  • Clinical advantages:
    • Better visualization: Clear, tactile 3D models improve understanding of anatomy for healthcare teams and patients.
    • Optimized care pathways: Enables more precise planning and enhances informed consent.
    • Cost-effective delivery: Accessible through Axial3D’s platform, without major investment in on-site printing infrastructure

Why It Matters

By combining GE HealthCare’s MRI innovations with Axial3D’s automated segmentation, this collaboration proves how advanced 3D modeling:

  • Enhances clinical decision-making.
  • Deepens patient and team communication.
  • Multi-tissue modeling (soft-tissue nerves + bone) highlights the flexibility and precision of our solution.
  • Real-world clinical benefit—helped avoid surgery and accelerated recovery—reinforces the value of Axial3D models in care pathways.